SR9011 vs SARM  

SR 9011 is a lab-synthesized compound that is essentially a nuclear receptor REV - ERB agonist .  

SARM is a class of experimentally synthesized compounds known as selective androgen receptor modulators .  

It is clear that the SR 9011 and SARM are fundamentally different .  

S 23 and RAD 140 are the major SARMS , which are highly potent and closer to anabolic steroids .  SARM compounds selectively bind to androgen receptors in bone and muscle tissue to regulate muscle mass and bone health .  

 

Although SR 9011 and SARM are not identical in nature , when bodybuilder uses SR 9011 for bodybuilding , SR 9011 is usually classified as SARMs ,  This is because SR 9011 for bodybuilding plays a similar role to SARM for bodybuilding .  

While most SARMs act by binding to androgen receptors in the body's muscle or bone tissue , SR 9011 acts by binding to the nuclear receptor REV - ERB in the hypothalamus , skeletal muscle , liver and adipose tissue .  SR 9011 produces changes at the cellular level that rewrite DNA expression in a unique way .  By turning genes on and off , SR 9011 affects glucose production , fat cell growth and regulates the body's natural circadian rhythms .  This is actually SR 9011 , which is what SR 9009 was developed for . 

How does it works when use SR 9011 for Bodybuilding ?  

SR 9011 is a nuclear receptor REV - ERB agonist , and to understand how SR 9011 works , you need to start with the nuclear receptor REV - ERB .  

This intracellular receptor is a protein molecule located in the nucleus . The nuclear receptor REV-ERB protein is responsible for a variety of functions in the body , including energy , carbohydrate and fat metabolism , which depend on nuclear receptor REV - ERB .  

We know that the intensity of physiological processes changes over the course of a day .  Metabolism speeds up during the day and slows down at night , reaching its lowest level late at night .  The rhythm of daily activity is called the circadian rhythm .  

The mammalian biological clock is composed of a master clock , located in the Suprachiasmatic nucleus (SCN) of the hypothalamus , and a peripheral clock , which acts as a pacemaker for circadian rhythms and coordinates cellular oscillators throughout the body through neural and hormonal signals .  The peripheral biological clock is distributed in various tissues and organs , such as liver , kidney , heart and muscle , and has certain independence .  

Circadian rhythms are regulated by many mechanisms , including nuclear receptors .  REV - ERB  is one such regulator .  

REV- ERB activation leads to the expression of genes encoding proteins of enzymatic systems involved in metabolic processes .  Under natural conditions , REV - ERB activity increases during the day and decreases at night , as indicated by the above basal metabolic rate changes .  

SR 9011 is a nuclear receptor REV - ERB modulator . As an agonist for this nuclear receptor , SR 9011 promotes the activity of genes that affect the rate of metabolic processes . Regardless of the time of day , use of SR 9011 is accompanied by an increase in the rate of energy , lipid , and carbohydrate metabolism .  Basal metabolic indexes were increased , and the decomposition of fatty acids and glucose in aerobic ATP synthesis was accelerated . 

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