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Description

Applications of Nisin

Nisin has been approved for use as a food preservative in several countries, including the United States, Canada, and Europe. It is commonly used in cheese, meat, and canned food products to extend their shelf-life and prevent spoilage. Nisin is also used in the production of beverages, such as beer and wine, to prevent contamination by spoilage bacteria. In addition, Nisin has potential applications in the pharmaceutical industry, where it could be used to prevent the growth of pathogenic bacteria in medical devices and drugs.

Health Benefits of Nisin

In addition to its antimicrobial activity, Nisin has been found to have several potential health benefits. Studies have shown that Nisin can inhibit the growth of cancer cells, including breast, colon, and liver cancer cells. It does this by inducing apoptosis, or programmed cell death, in cancer cells. Nisin has also been shown to have immunomodulatory effects, which could help to boost the immune system and prevent infections. Furthermore, Nisin has been shown to have anti-inflammatory effects, which could be beneficial for the treatment of inflammatory bowel disease and other chronic inflammatory conditions.

Safety of Nisin

Nisin has been extensively studied for its safety and toxicity, and it has been found to be safe for human consumption at levels typically used in food and beverage products. The Joint FAO/WHO Expert Committee on Food Additives (JECFA) has established an acceptable daily intake (ADI) for Nisin of 0-0.25 mg/kg body weight. This means that a person weighing 70 kg could safely consume up to 17.5 mg of Nisin per day without any adverse effects. Nisin is also considered safe for use in infant formula and other foods consumed by infants and young children.